Diazepam in Oral-surgery: Analysis of Variation in Blood-glucose and Blood-pressure

Objectives: Evaluate the variations of blood pressure and blood glucose in patients undergoing dental surgery either using or not oral preoperative sedation with Diazepam
Methods: Sixty-eight adult patients of both sexes, aged between 18-76 years old, without systemic diseases and undergoing dental extraction procedures with local anesthetic (lidocaine 2% with epinephrine 1/100 000), took part in this study. The patients were divided into two groups: G1 (using oral diazepam 5mg) and G2 (control). There were blood pressure values ​​(BP3BK1 / G-TECH FREE) and blood glucose (G-TECH FREE) performed ​​initial and final surgical procedures. Anxiety was recorded by Rating Scale Corah. Collected data were recorded in a spreadsheet program Excel XLS® and subjected to statistical (Test-T; Mann-Whitney,p<0.05).
Results: Systolic Blood Pressure (SBP): Analysis of initial and final SBP between medicated and control groups showed that there was significant increase in SBP (p=0,000.) in the control group.
Diastolic Blood Pressure (DBP): Final pressure was significantly increased between the groups (p=0.017). Evaluating the variation of the initial and final DBP within the same group did not show variations in the medicated group and a significant increase in the control group at the final moment (p=0.025).
Capillary blood glucose: There were no differences between groups or between the initial and final times of each group
Conclusions: Arterial Systolic and diastolic blood pressure in patients who used diazepam remained constant until the end of the procedure, indicating the protective role of this drug in dental procedures.
The occasional use of diazepam did not affect the variation in blood glucose during surgery.