Gingivitis and Salivary Cytokines in a Group of PR Adolescents
Objectives: The aim of this cross sectional study was to evaluate the prevalence of gingivitis and its association to salivary cytokines and obesity in a group of Puerto Rican (PR) adolescents.
Methods: A convenience sample of 135 Puerto Rican (PR) adolescents ages 13 to 18 years from 3 PR public schools was recruited. The University of Puerto Rico’s IRB approved the study. A one visit dental evaluation was performed at the schools by a calibrated dentist. This evaluation included plaque index, ICDAS caries exam, bleeding on probing, probing pocket depth, and recession. Height, weight and waist circumference were measured. Five ml of saliva samples were taken for analysis of 10 cytokines : (Il-b, MMP-8, MMP-9, OPG, TRANCE, TNF alpha, leptin, adenopectin, CRP, IL-6, Periostin). Four periapical radiographs were taken. A behavioral risk questionnaire was administered. Statistical analysis was performed using SPSS.
Results: Participants distribution were: obese (32%), overweigh t(16%), healthy weight (50%) and underweight (2%); females were 60%. Gingivitis was defined as 20% or more sites with bleeding on probing. Prevalence of gingivitis for the total sample was 25.19% Gingivitis was found in 12% of obese, 2% overweight and 11.19 % of healthy weight. No statistically significant findings were found for obesity and gingivitis (p> 0.05). Multiple regression analysis controlling for age, gender and BMI found no salivary cytokines levels were related to gingivitis except for a trend in the levels of leptin (p = 0.205).
Conclusions: The results of this study showed an important finding of inflammation in gums in adolescents but could not show expression in the levels of specific salivary cytokines.
Division: IADR/AADR/CADR General Session
Meeting:2015 IADR/AADR/CADR General Session (Boston, Massachusetts) Location: Boston, Massachusetts
Year: 2015 Final Presentation ID:4520 Abstract Category|Abstract Category(s):Oral Health Research
Authors
Maldonado, Linette
( University of Puerto Rico School of Dental Medicine
, San Juan
, Puerto Rico
, United States
)
Lopez Del Valle, Lydia
( University of Puerto Rico School of Dental Medicine
, San Juan
, Puerto Rico
, United States
)
Hanke Herrero, Rosana
( University of Puerto Rico School of Dental Medicine
, San Juan
, Puerto Rico
, United States
)
Muñoz-torres, Francisco
( University of Puerto Rico School of Dental Medicine
, San Juan
, Puerto Rico
, United States
)
Taylor, George
( University of San Francisco School of Dentistry
, San Francisco
, California
, United States
)
Support Funding Agency/Grant Number: Puerto Rico Trust of Research and Technology and Colgate Palmolive Research Donation Award
Financial Interest Disclosure: The presenter has no conflict of interest neither financial interest