IADR Abstract Archives
Xenogenic Collagen Martrix for the Treatment of Gingival Recession
Objectives: The aim of this study was to compare the one-year outcomes for root coverage procedures of Miller Class I and II defects in the anterior maxilla using either the gold standard connective tissue graft (CTG) in combination with a coronally advanced flap (CAF) or a bi-layered xenograph collagen matrix (CM) in combination with CAF, establishing if CM + CAF offers a predictable, equivalent alternative to CTG + CAF.
Methods: Ten non-smoker (3 male and 7 female; mean age 39.3 +/- 9.2 years) with contra-lateral Miller Class I or II recession defects in the maxillary anterior were included in this randomized, split-mouth study. Sites were randomly assigned for treatment to either CAF + CTG (palatal connective tissue graft) or CAF + CM (MucograftÒ, a bi-layered demineralized collagen matrix). Sites were examined at baseline, 6 months and 12 months postoperatively. The outcome measures were recession depth, gain in clinical attachment, increase in keratinized tissue and gingival tissue thickness.
Results: At 12 months both CAF + CTG and CAF + CM resulted in a significant reduction in recession (2.57mm vs 2.41mm), a gain in gain of attachment (2.1mm vs 2.36mm) and increase in keratinized tissue (2.25mm vs 2.35mm), with no statistically significant differences between the two groups. CAF + CTG demonstrated a statistically significant increase in gingival tissue thickness, while no significant increase was noted in the CAF + CM group (1.58mm vs. .20 mm).
Conclusions: For Miller Class I and II defects on maxillary incisors and bicuspids, a bi-layered xenograph collagen matrix plus a coronally advanced flap provides an alternative to the gold standard connective tissue graft and coronally advanced flap while minimizing the possibility of bleeding, pain and infection that can be associated with a palatal soft tissue graft donor sites.
Methods: Ten non-smoker (3 male and 7 female; mean age 39.3 +/- 9.2 years) with contra-lateral Miller Class I or II recession defects in the maxillary anterior were included in this randomized, split-mouth study. Sites were randomly assigned for treatment to either CAF + CTG (palatal connective tissue graft) or CAF + CM (MucograftÒ, a bi-layered demineralized collagen matrix). Sites were examined at baseline, 6 months and 12 months postoperatively. The outcome measures were recession depth, gain in clinical attachment, increase in keratinized tissue and gingival tissue thickness.
Results: At 12 months both CAF + CTG and CAF + CM resulted in a significant reduction in recession (2.57mm vs 2.41mm), a gain in gain of attachment (2.1mm vs 2.36mm) and increase in keratinized tissue (2.25mm vs 2.35mm), with no statistically significant differences between the two groups. CAF + CTG demonstrated a statistically significant increase in gingival tissue thickness, while no significant increase was noted in the CAF + CM group (1.58mm vs. .20 mm).
Conclusions: For Miller Class I and II defects on maxillary incisors and bicuspids, a bi-layered xenograph collagen matrix plus a coronally advanced flap provides an alternative to the gold standard connective tissue graft and coronally advanced flap while minimizing the possibility of bleeding, pain and infection that can be associated with a palatal soft tissue graft donor sites.