IADR Abstract Archives
Application of Paste Containing S-PRG Filler to Prevent Enamel Demineralization
Objectives: Poor oral hygiene due to bad brushing techniques can lead to enamel demineralization. Surface pre-reacted glass-ionomer (S-PRG) technology, forming a stable glass-ionomer phase in fillers, was introduced recently and the S-PRG fillers show the ability to release multiple ions. The purpose of this study was to determine if a new experimental paste containing S-PRG filler can prevent enamel demineralization.
Methods: One hundred embedded human enamel blocks was ground using 600-grit sandpaper and polished using diamond suspensions. The specimens were subjected to alternating immersion in demineralizing (pH 4.55) and remineralizing (pH 6.8) solutions for 14 days. During the immersion, all specimens were brushed twice per day using two different pastes (0% or 5% S-PRG) and two different pastes (5% or 30% S-PRG) were applied (simulating tray method) for 10 minute (2 or 5 times per week) before immersion in demineralizing solution. Nanoindentation testing was carried out (ENT-1100a, ELIONIX) using three loading conditions (10, 100, and 300 mN) before and after alternating immersion (n=10). Mean values for hardness and elastic modulus were compared using Kruskal-Wallis and Mann-Whitney U tests (P < 0.05). To estimate acid-neutralizing ability, fourfold diluted solution of S-PRG filler-containing paste (0.025g) was added to lactic acid solution (20mL, pH=4.6), and time-dependent pH change in the solution was measured using a pH meter.
Results: The values of hardness and elastic modulus for specimen brushed using paste without S-PRG filler and without tray method significantly decreased after alternating immersion, while the values were stable for specimens brushed using paste with S-PRG and applied tray method using paste containing S-PRG filler. Addition of S-PRG filler containing paste to lactic acid solution caused increasing the pH. These results suggest that the acid buffer capacity of paste containing S-PRG filler may help to inhibit enamel demineralization.
Conclusions: New experimental S-PRG filler-containing paste can prevent enamel demineralization.
Methods: One hundred embedded human enamel blocks was ground using 600-grit sandpaper and polished using diamond suspensions. The specimens were subjected to alternating immersion in demineralizing (pH 4.55) and remineralizing (pH 6.8) solutions for 14 days. During the immersion, all specimens were brushed twice per day using two different pastes (0% or 5% S-PRG) and two different pastes (5% or 30% S-PRG) were applied (simulating tray method) for 10 minute (2 or 5 times per week) before immersion in demineralizing solution. Nanoindentation testing was carried out (ENT-1100a, ELIONIX) using three loading conditions (10, 100, and 300 mN) before and after alternating immersion (n=10). Mean values for hardness and elastic modulus were compared using Kruskal-Wallis and Mann-Whitney U tests (P < 0.05). To estimate acid-neutralizing ability, fourfold diluted solution of S-PRG filler-containing paste (0.025g) was added to lactic acid solution (20mL, pH=4.6), and time-dependent pH change in the solution was measured using a pH meter.
Results: The values of hardness and elastic modulus for specimen brushed using paste without S-PRG filler and without tray method significantly decreased after alternating immersion, while the values were stable for specimens brushed using paste with S-PRG and applied tray method using paste containing S-PRG filler. Addition of S-PRG filler containing paste to lactic acid solution caused increasing the pH. These results suggest that the acid buffer capacity of paste containing S-PRG filler may help to inhibit enamel demineralization.
Conclusions: New experimental S-PRG filler-containing paste can prevent enamel demineralization.