IADR Abstract Archives

Core Clinical Research and Statistical Concepts Specific topics include: Defining the research question Causation vs. association Sources of error in clinical research Multiple outcomes: primary and secondary outcome measures Basics and benefits of clinical trials/intervention studies Study Populations Randomization Masking / Blinding - whom and why Intention To Treat (ITT) & per-protocol statistical analyses Use of biomarkers and surrogate measures Superiority, equivalence & non-inferiority Introduction to multivariable statistical modeling Linear regression Regression of dichotomies and counts Survival regression Management of simple confounding and effect modification via regression models