Electrochemical corrosion and bacterial adhesion study of Two Osteosynthetic Plates
Objectives: The aim of the present in vitro study was threefold: first; to evaluate the novel Pakistani manufactured osteosynthetic titanium bone mini plates (MPP) used for mandibular fracture fixation in terms of electrochemical and biological characterizations; second to compare this material with an international brand (Germany) (MPG); and third to have an overall comparison of both plates in order to have a better alternative to internationally available expensive plates. Methods: Electrochemical study of MPP and MPG was carried out through Tafel extrapolation curves using Gamry® electrochemical framework in modified simulated body fluid (mSBF) prepared with pH 7.4 at 37o.C. For bacterial adhesion experiment the bacterial culture (Staphylococcus aureus) of 50 μl with an OD600 of 1.0, which corresponds to approximately 1.79×109 cells ml-1, was used. Cfu per unit plate and SEM were done to access bacterial adhesion. The data was analyzed by pair T test by using SPSS software version 20.
Results: It was concluded that corrosion resistance behavior of MPP and MPG is not significantly different (P≥0.05) but in case of bacterial adhesion the local plates showed significantly low (P 0.05) adhesion as compared to imported material. Overall the biocompatible properties of local plates meet international brand qualities Conclusions: This study proves to be beneficial for poor patients of facial fractures who cannot afford three times expensive imported plates as compared to local plates.