Clinical Efficacy in Plaque/Gingivitis of Colgate Total vs. Parodontax

Method: Prior to the study the clinical protocol was reviewed and approved by IRB. The study had a randomized, double-blind, parallel-group design.  Subjects who had initial Quigley-Hein plaque index at least 1.5 and initial Loe-Silness gingival index at least 1.0 participated in the study.  Subjects were assessed at baseline, 3 months and 6 months of product use. 

Result: A total of 135 subjects completed the study in Thailand.  At baseline, no significant differences in plaque and gingivitis scores were indicated among the three groups.

At 3 months, CT, PD and NC groups showed plaque scores 2.45, 3.45 and 3.31; and gingivitis scores 1.27, 1.67 and 1.63, respectively. CT group provided significantly greater reductions than PD group in plaque (29.0%) and gingivitis (24.0%); and NC group in plaque (26.0%) and gingivitis (22.1%).  There were no significant differences in plaque and gingivitis reductions between PD and NC groups.

At 6 months, CT, PD and NC groups showed plaque scores 1.65, 3.23 and 3.40; and gingivitis scores 0.95, 1.47 and 1.57, respectively.  CT group provided significantly greater reductions than PD group in plaque (48.9%) and gingivitis: (35.4%); and NC group in plaque (51.5%) and gingivitis (39.5%).  There were no significant differences in plaque and gingivitis reductions between PD and NC groups.

Conclusion: The study results demonstrated that Colgate Total Toothpaste is significantly more effective in reducing plaque and gingivitis than Parodontax Toothpaste after 3 and 6 months product use.