Methods: In 190 pregnant women, we measured GCT values, periodontal disease parameters, and covariates.
Results: Higher GCT values were significantly correlated with age as well as bleeding on probing - BOP (for both, r = 0.30, p = 0.003). Women who had higher BOP values (greater than the 75thpercentile of the distribution) also had significantly higher GCT values (OR = 3.6; 95% CI = 1.3-10.1), a finding that remained significant even after controlling for age (OR = 3.5; 95% CI = 1.2-10.4). The association between the percentage of sites with greater than 3 or 4mm pockets with GCT values were also significant after controlling for age, percentage of BOP, and pre-pregnancy BMI (p=0.002 and 0.0006, respectively).
Conclusion: Pregnant women with more bleeding on probing and more sites with greater than 3 or 4mm pockets seem to have higher GCT values independent of potential confounders, findings that lend credibility to the association between periodontal disease and GDM.