Syria is one of the countries were the population has an easy access to the antibiotics, and the antibiotics consumption is therefore uncontrolled. The aim of this in vitro study was to define the most effective antibiotics against the bacteria that cause odontogenic abscesses within Syrian population, and if possible to provide some recommendation about the most effective regimen of antibiotics to be prescribed .
Method:
Thirty five random patients were involved in the study. Pus specimens were aspirated from the infected area (capsule of the abscess). Samples of the collected pus were spread onto a plate of nutrient Broth, blood agar, and EMB media under two incubation conditions (aerobic and anaerobic); colonies identity and antibiotic sensitivity were determined by means of Foenix 100 and by the conventional technology. Thirty five antibiotics were studied.
Result:
Kruskal-Wallis test revealed significant difference (p<0.001) in the antibiotics sensitivity rates in general, and Mann-Whitney U revealed also significant differences for most cases when each of the studied antibiotics compared with the others.
Conclusion:
This study revealed that Streptococcus was the most isolated bacteria, Levofloxacin and Moxifloxacin were the most effective antibiotics, whereas the other antibiotics revealed notable decreased efficacy specially Betalactams.