Method: Twenty seven young patients with non-vital, immature maxillary central incisors were randomly categorized into 3 groups. Following the chemo-mechanical preparation and canal disinfection with triple antibiotic paste, it was filled with whole blood, PRF and PRP in groups 1, 2 and 3 respectively. The cases were followed up clinically and radiographically at 6, 12 and 24 month intervals. Periapical healing was evaluated using periapical index scores . Root lengthening, canal wall thickening, apical closure and apical response index were also compared and statistically analysed
Result:
Clinically, all cases were asymptomatic with complete resolution of signs and symptoms. More number of cases revascularized with PRP showed positive response to vitality. Radiographically, PRP group was comparatively better in periapical healing, dentinal wall thickening and apical closure, though not statistically significant. Type I apical response was found to be common in group 2 and 3.
Conclusion:
Revascularization with PRP can be considered as a better biological scaffold as it has the potency to improve the desired biological outcome.