Longitudinal Study of Monitoring Efficiency in Salivary Multi-test System
Objective: In order to achieve a comprehensive oral health assessment, a new salivary multi-test system has been developed. This system can assay seven saliva analytes measuring color changes of the test strip as reflectance: [Dental caries] cariogenic bacteria (activity), pH, buffer capacity, [Periodontal disease] blood, leukocyte, protein, [Oral cleanliness] ammonia. In our previous cross-sectional study, we found that the reflectance of each analyte was highly correlated with oral conditions (2013 IADR General Session). In this longitudinal study, we evaluated the monitoring efficiency of this system by observing how the reflectance followed the changes of oral conditions with time through active oral care.
Method: 57-subjects (50.3±12.6y) of 5-dental offices were examined at baseline and after 1, 3 and 6 months. During each visit, oral rinse samples (3ml-DW, 10sec-rinse) were collected and 10μl of the sample was dropped onto the strip, and the reflectance was measured. After collecting samples, the oral conditions, such as plaque control record (PCR), probing depth and total number of bacteria were measured. The changes of oral conditions were compared with those of the reflectance at every visit, and the correlation between them was assessed (Spearman, p<0.05).
Result: [Dental caries] Cariogenic bacteria showed parallel changes with PCR, while pH and buffer capacity did not. There was no correlation between these analytes and PCR. [Periodontal disease] The changes of probing depth were followed by those of blood, leukocyte and protein. They were significantly correlated with probing depth during each visit. [Oral cleanliness] Ammonia exhibited parallel change with total number of bacteria during each visit indicating significant correlation between them.
Conclusion: It was revealed that the changes of oral conditions through active oral care were followed by the reflectance measured by the salivary multi-test system. From these results, this system was shown to be useful for monitoring oral health.
Division: IADR/AMER General Session
Meeting:2014 IADR/AMER General Session (Cape Town, South Africa) Location: Cape Town, South Africa
Year: 2014 Final Presentation ID:1584 Abstract Category|Abstract Category(s):Oral Health Research
Authors
Nishinaga, Eiji
( Lion Corporation, Tokyo, , Japan
)
Suzaki, Akira
( Department of Operative Dentistry, School of Dentistry, Aichi Gakuin University, Nagoya, , Japan
)
Arimoto, Norihiro
( Department of Operative Dentistry, School of Dentistry, Aichi Gakuin University, Nagoya, , Japan
)
Matsui, Osamu
( Department of Operative Dentistry, School of Dentistry, Aichi Gakuin University, Nagoya, , Japan
)
Gomi, Akira
( Department of Operative Dentistry, School of Dentistry, Aichi Gakuin University, Nagoya, , Japan
)
Fujitani, Morioki
( Department of Operative Dentistry, School of Dentistry, Aichi Gakuin University, Nagoya, , Japan
)
Senda, Akira
( Department of Operative Dentistry, School of Dentistry, Aichi Gakuin University, Nagoya, , Japan
)
Uchiyama, Chiyoko
( Lion Corporation, Tokyo, , Japan
)
Takagi, Yuuki
( Lion Corporation, Tokyo, , Japan
)
Saito, Koichi
( Lion Corporation, Tokyo, , Japan
)
Yamamoto, Takashi
( Lion Foundation for Dental Health, Tokyo, , Japan
)
Murakoshi, Michiaki
( Lion Corporation, Tokyo, , Japan
)
Fukuta, Isao
( ARKRAY Inc, Kyoto, N/A, Japan
)
Okubo, Akio
( ARKRAY Inc, Kyoto, N/A, Japan
)
Takahashi, Kyosuke
( Department of Operative Dentistry, School of Dentistry, Aichi Gakuin University, Nagoya, , Japan
)