IADR Abstract Archives

Detection Of H2o2 Permeation In Dental Structures By Eletrochemical Methods

Objective:  To evaluate the time of diffusion of hydrogen peroxide in tooth structures using an in vitro permeation methodology of electrochemical analysis

Method: Eighteen (N = 18) bovine incisors were randomly divided into groups: G1: placebo (n = 8) and G2 = hydrogen peroxide 35% (n = 10). All specimens had the lingual surface (enamel and dentin) removed with water sandpaper, granulation 180. Buccal dentin was preserved and buccal enamel suffered wear to standardize the thickness of the specimens at 3.5 mm. Preparation of samples involved setting it with acrylic resin. The bucal and pulp were isolated, preventing the permeation of other materials in other ways. Gels (G1) or (G2) were applied on the labial enamel side of the specimens and the maximum permeation was 3600 seconds. This method was repeated three times (T1, T2 e T3) with each specimen, being a week the gap time. The microelectrode was located in the pulp chamber and  was calibrated to detect H2O2 and measure the peroxide.

Result: : Analysis of variance (ANOVA) demonstrated difference between the permeation of hydrogen peroxide and placebo (p = 0.01). During the study,  electrochemical analysis did not identify any electrical current (nA) for placebo, however hydrogen peroxide was identified with median time to the beggining of detectable molecules  in the pulp chamber, 1148 sec (i=1,024 nA) Regarding the  measurement repetition , the average time to permeation  were: T1= 1841 sec, T2= 1094 sec  and T3= 510 sec. T1 differ to T2 and T3 (p = 0.0005), however T2  to T3 was similar (p> 0.05).

Conclusion: The electrochemical analysis by microelectrode  is effective for detecting  peroxide molecules within the pulp camera. The difference between the moments of detection indicate that the permeability across tooth structures suffers changes due each passage of hydrogen peroxide, the average time to reach the pulp chamber decreases.

Division: IADR/AADR/CADR General Session
Meeting: 2013 IADR/AADR/CADR General Session (Seattle, Washington)
Location: Seattle, Washington
Year: 2013
Final Presentation ID: 501
Abstract Category|Abstract Category(s): Late-breaking News
Authors
  • Nishida, Alexander  ( Universidade de São Paulo, São Paulo, , Brazil )
  • Francci, Carlos  ( Universidade de São Paulo, São Paulo, , Brazil )
  • Bertotti, Mauro  ( Universidade de São Paulo, São Paulo, N/A, Brazil )
  • Castro, Pollyana  ( Universidade de São Paulo, São Paulo, N/A, Brazil )
  • SESSION INFORMATION
    Poster Session
    Late-breaking News
    03/21/2013