The objective of this study was to assess the extent to which Philips Sonicare DiamondClean (PSDC) differs in single-use plaque reduction versus Oral-B Triumph Floss Action (OBT).
Method:
A randomized, examiner blinded, 4 visit crossover-design study was conducted in a population of healthy adults aged 18-65 years. At Visit 1, Informed Consent was obtained and subjects were screened for enrollment. Eligible subjects were manual toothbrush users with a minimum plaque accumulation screening score of >1.8 per Modified Quigley Hein Plaque Index (MQH) examination. At Visit 2, subjects were randomized to a treatment sequence. Subjects were dispensed products for an acclimation period of use of approximately 6 brushings x 3 Days with PSDC or OBT. Acclimation was followed by a wash-out period with MTB for all subjects. Subjects returned for Visit 3 efficacy evaluation at Day 7 (±1 day) with 24 hours plaque accumulation. An MQH score was assessed followed by supervised product use per randomization and post-brushing MQH score. Subjects then crossed to the second sequence of product use and repeated at-home procedures. The final efficacy assessment at V4 included repeat pre and post brushing MQH assessments. Safety was characterized in intraoral exams and per subject diary report. A linear mixed effects model was used for statistical analysis.
Result:
Ninety-nine subjects completed the study (67 females, 32 males; mean age 37 years). Overall LSMean(SE) pre-brushing MQH scores were 3.9(0.04) for PSDC and 3.9(0.04) for OBT; post-brushing values were 0.7(0.04) for PSDC and 0.8(0.04) for OBT. The observed difference is statistically significant (p=0.0059).
Conclusion:
PSDC power toothbrush was statistically significantly superior to OBT power toothbrush overall in reducing surface plaque. Both products were safe for use.