Method: Bovine enamel specimens were distributed into 10 groups (n=12): experimental placebo toothpaste (no F); NaF (1450 ppm F); TiF4 (1450 ppm F); SnF2 (1450 ppm F); SnF2 (1100 ppm F) + NaF (350 ppm F); TiF4 (1100 ppm F) + NaF (350 ppm F); commercial toothpaste Pro-Health (SnF2-1100 ppm F + NaF-350 ppm F, Oral B); commercial toothpaste Crest (NaF-1.500 ppm F, Procter & Gamble); abrasion without toothpaste; and only erosion. The erosion was performed 4x90s/day (Zero Sprite). The toothpastes’ slurries were applied and the specimens abraded using electric toothbrush, 2x15s/day. Between erosive and abrasive challenges, the specimens remained in artificial saliva. After 7 days, the enamel wear was evaluated using profilometer (µm). The data were statistically analyzed using ANOVA followed by Tukey`s test (p<0.05).
Result: The experimental toothpastes containing NaF, TiF4 and SnF2 and Pro-health showed a significant reduction in enamel wear (between 42-54% compared to placebo). The toothpastes with SnF2/NaF and TiF4/NaF showed the best results in the reduction of enamel wear (between 62-70% compared to placebo) (p<0.05). The commercial NaF toothpaste was unable to reduce enamel wear (p>0.05).
Conclusion: Therefore, the experimental toothpastes containing both conventional and metal fluoride seem to be promising to reduce enamel wear in vitro.