IADR Abstract Archives

Evaluation of Antibacterial Activity in a Selenium Containing Orthodontic  Resin

Objectives:   Fixed orthodontic treatment may provide accumulation sites for cariogenic bacteria around the brackets, possibly leading to white spot lesions. Resin based orthodontic bonding materials are mostly preferred but they may permit further bacterial attachment and growth. Inclusion of selenium compound to resin was suggested to introduce antibacterial properties that would help inhibit bacterial colonization around the brackets. The aim of this in-vitro study was to compare the antibacterial property of a selenium-containing orthodontic resin(SeD) with a standard resin(XT) and a resin-modified-glass-ionomer(RMGI). 

Methods: Three orthodontic materials were tested(SelectDefense/Element34TechnologyInc; TransbondXT/3MUnitek; Fuji Ortho-LC/GCAmerica). Evaluation of antibacterial properties utilized bacterial growth in liquid media(BG) and agar diffusion(AD) tests.  In BG, each material included 100 adhesive discs(3x2mm) divided into groups of five in vials together with 0.5ml of brain-heart-infusion broth and 2.5µl of streptococcus mutans(MS)(n=20).  Following incubation(37°C,24hours), bacterial growth was measured using a Spectrophotometer(Genesys 20) at 600nm for optical density(OD).  In AG, agar plates were inoculated with 100µl of MS in brain heart infusion agar. Fifteen adhesive discs(6x2mm) of each material were prepared and placed in groups of five in 3 agar plates.  Following incubation(37°C,48hours), the agar plates were visually inspected for zones of bacterial inhibition. Results were statistically analyzed with One way ANOVA using Tukey’s HSD test for all multiple comparisons. 

Results:  In BG, selenium containing resin(SeD) promoted more bacterial growth(OD=0.427/StandardDeviation(SD)==0.081) compared to the standard-resin(XT)(OD= 0.222/SD=0.083) and RMGI(OD=0.275/SD=0.093) but less growth compared to the positive-control(OD=0.522/SD=0.070). The differences were statistically significant(pConclusions: Within the limitations of this in-vitro study, selenium containing orthodontic resin was less effective inhibiting bacterial growth compared to the widely used standard resin and RMGI. None of the materials, including fluoride-releasing RMGI, caused bacterial inhibition in their surroundings.

Division: IADR/AADR/CADR General Session
Meeting: 2013 IADR/AADR/CADR General Session (Seattle, Washington)
Location: Seattle, Washington
Year: 2013
Final Presentation ID: 188
Abstract Category|Abstract Category(s): Dental Materials 7: Polymer-based Materials-Physical Properties and Performance
Authors
  • Nguyen, James  ( Nova Southeastern University, Fort Lauderdale, FL, USA )
  • Kilinc, Evren  ( Nova Southeastern University, Fort Lauderdale, FL, USA )
  • Garcia-godoy, Cristina Elizabeth  ( Nova Southeastern University, Fort Lauderdale, FL, USA )
  • Burch, James  ( Nova Southeastern University, Fort Lauderdale, FL, USA )
  • Hardigan, Patrick  ( Nova Southeastern University, Fort Lauderdale, FL, USA )
  • Shelling, Pamela  ( Nova Southeastern University, Fort Lauderdale, FL, USA )
  • SESSION INFORMATION
    Oral Session
    Antimicrobial Effects and Biocompatibility
    03/20/2013