IADR Abstract Archives

Gingival Biotype Enhancement with Acellular Dermal Matrix Allografts

Objectives: Acellular dermal matrix allograft (ADMA) has been hypothesized to create a zone of “immobile tissue” extending apical to the mucogingival junction (MGJ) in the treatment of gingival recessions. This project aims to investigate the presence of this zone associated with the use of a coronally advanced flap in combination with one of 2 types of ADMA for root coverage procedures.  

Methods: Twenty patients (Miller Class I or II recession defects) were randomized to receive either ADMA-A or -B. Further randomization was done in the ADMA-B group regarding the orientation of the basement membrane (BM) of the graft, “toward” or “away from” the root surface. Clinical assessments of plaque index (PI), gingival index (GI), probing depth (PD), clinical attachment level (CAL), recession depth (RD) and width (RW), width of keratinized gingiva (KG), gingival thickness (GT1 and GT2) and width of immobile tissue (IT) were evaluated between baseline and 12 months postoperatively.   

Results: PI, GI, PD, CAL and KG were comparable between groups. The average root coverage was 63% with ADMA-A and 81% with ADMA-B. The zone of IT extended apical to MGJ by a mean of 1.88mm in the ADMA-A group and 2.69mm in the ADMA-B group. No statistically significant differences were noted for the abovementioned parameters (Mixed model, P>0.05). Following the same statistical model, GT1 was only increased with ADMA-A by a mean of 0.92mm and placing BM “away from” rather than “toward” the defect resulted in a 1mm gain in IT and 0.59mm loss of GT1 in the ADMA-B group (P<0.05).  

Conclusions: The use of either type of ADMA results in predictable root coverage. This study provides novel evidence on the presence and quantity of a zone of immobile tissue extending apical to MGJ. Hence, minimal or no KG at baseline should not preclude the use of ADMA.

Division: IADR/AADR/CADR General Session
Meeting: 2013 IADR/AADR/CADR General Session (Seattle, Washington)
Location: Seattle, Washington
Year: 2013
Final Presentation ID: 915
Abstract Category|Abstract Category(s): Periodontal Research - Therapy
Authors
  • Abou-arraj, Ramzi  ( University of Alabama at Birmingham, Birmingham, AL, USA )
  • Geisinger, Maria L.  ( University of Alabama at Birmingham, Birmingham, AL, USA )
  • Vassilopoulos, Philip John  ( University of Alabama at Birmingham, Birmingham, AL, USA )
  • Reddy, Michael  ( University of Alabama at Birmingham, Birmingham, AL, USA )
  • Geurs, Nicolaas C.  ( University of Alabama at Birmingham, Birmingham, AL, USA )
  • SESSION INFORMATION
    Poster Session
    Periodontal Surgery and Mucogingival Therapy
    03/21/2013