Objective: This study evaluated the antioxidant activity and anti-radical of methanolic crude extract of the leaves of sweet-potato (Ipomoea batatas) and its toxicity.
Method: The tests for antioxidant activity were ABTS • +, DPPH, HOCl and superoxide anion, which presented results for maximum inhibition of 99.8% (35.7µg/mL), 93.7% (120µg/mL), 54.8% (40µg/mL) and 30.2% (0.04µg/mL), respectively.
Result: The toxicity of the extract was evaluated by testing alternative lethal concentration 50 (CL50) with Artemia salina, which was estimated by the statistical method of Probit and regression analysis, with a 24h: CL50=286.39µg/mL and 48h: CL50=194.47µg/mL.
Conclusion: It was observed that the methanol extract from leaves of sweet potato has a higher potential as a source of compounds with antioxidant and anti-radical, and for toxicity, there is a linearity of the concentration-response relationship.